ExiTronâ„¢ BAT

CT agent for imaging of brown fat

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ExiTronâ„¢ BAT CT contrast agent (1 x 5 injections): 130 - 095 - 707
ExiTronâ„¢ BAT CT contrast agent (5 x 5 injections): 130 - 095 - 708

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ExiTron BAT is an innovative agent optimized for in vivo CT studies of brown adipose tissue (BAT) in small animals. Containing an iodine-based amphiphile, it accumulates in brown fat deposits enabling accurate identification of this tissue with ease.

ExiTron BAT, the unique CT agent:

  • Shows a high accumulation in the BAT of small animals
  • Delivers optimal CT contrast
  • Enables a wide imaging time window
  • ExiTron BAT is Viscover's leading agent for CT studies of brown fat

Apply ExiTron BAT to:

  • Effectively visualize brown fat, e.g. interscapular and cervical BAT
  • Quantify BAT volume
  • Longitudinally monitor changes in BAT morphology
Physico-chemical properties and structure
Mean hydrodynamic diameter:

~320 nm

Hounsfield units (undiluted agent):

~8000 HU

Schematic diagram of an ExiTron BAT

ExiTron BAT CT of brown adipose tissue (BAT)

Left: Sagittal CT image of a mouse at 3.5 hours post injection of ExiTron BAT showing contrast enhancement in the intrascapular BAT

Right: Timecourse of ExiTron BAT uptake in BAT of young mice with and without BAT activation via short-term cold exposure. Specifi c accumulation of the contrast agent in activated BAT enables visualization of this tissue with ease.

Sagittal CT image of a mouse at 3.5 hours post injection of ExiTron BAT showing contrast enhancement in the intrascapular BAT (red arrow).
Timecourse of ExiTron BAT uptake in BAT of young mice with and without BAT activation via short-term cold exposure. Specifi c accumulation of the contrast agent in activated BAT enables visualization of this tissue with ease.
Selected references
  1. Genger, C. et al. (2022) ExiTron BAT, a novel contrast agent visualising activated brown adipose tissue (BAT) by CT imaging. World Molecular Imaging Congress Meeting, Miami, USA.
Further information