Myocardial infarction

In vivo evaluation of a myocardial infarction in small animals using a novel CT blood pool imaging agent

In this study we report on an iodine-based nanoparticulate CT imaging agent, which provides optimal blood pool properties as well as high contrast enhancement in the myocardium. Due to the agent’s high iodine concentration and long blood half-life, enhanced vascular imaging can be performed where the vasculature can be visualized down to very fine vessel structures. In particular for myocardial imaging, the blood pool phase allows an estimation of functional parameters, e.g. the ejection fraction, while the enhancement phase allows for the estimation of infarct severity and size.

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