FeraSpin™ Series
Nanoparticle MRI research toolbox
FeraSpin™ XS MRI agent (1 x 5 injections): 130 - 095 - 140
FeraSpin™ XS MRI agent (5 x 5 injections): 130 - 095 - 141
FeraSpin™ S MRI agent (1 x 5 injections): 130 - 095 - 166
FeraSpin™ S MRI agent (5 x 5 injections): 130 - 095 - 167
FeraSpin™ M MRI agent (1 x 5 injections): 130 - 095 - 168
FeraSpin™ M MRI agent (5 x 5 injections): 130 - 095 - 169
FeraSpin™ L MRI agent (1 x 5 injections): 130 - 095 - 170
FeraSpin™ L MRI agent (5 x 5 injections): 130 - 095 - 171
FeraSpin™ XL MRI agent (1 x 5 injections): 130 - 095 - 172
FeraSpin™ XL MRI agent (5 x 5 injections): 130 - 095 - 173
FeraSpin™ XXL MRI agent (1 x 5 injections): 130 - 095 - 174
FeraSpin™ XXL MRI agent (5 x 5 injections): 130 - 095 - 175
The FeraSpin™ Series is a product family of six size-selected agents derived from FeraSpin R:
FeraSpin XS to FeraSpin XXL. The identical chemical composition and ultra-narrow size distribution of these fractions allow for fine-tuning of the pharmacologic profile according to your own innovative applications.
The unique series of size-selected superparamagnetic iron oxide (SPIO) nanoparticles:
- Is analogous to human clinical agents
- Encompasses particle fractions ranging from ultrasmall to large particle sizes
- Offers tunable T1 and T2/T2* relaxation properties
Apply the FeraSpin Series to
- Adjust your unique MRI contrast agent for extended circulation, or macrophage and organ-specific uptake by the liver and spleen
- Perform innovative in vitro and in vivo studies such as stem cell tracking, MR sequence development and Magnetic Particle Imaging (MPI)
Characteristics of the FeraSpin Series with respect to particle size

Blood half-life in rats of the different FeraSpin Series products in dependence of particle size

FeraSpin™ | Mean particle size (hydrodynamic diameter) | Relaxivity r2/r1 (in water 37 °C, 1.41 T ) |
---|---|---|
XS | 10 – 20 nm | 3 - 5 |
S | 20 – 30 nm | 5 - 9 |
M | 30 – 40 nm | 9 - 22 |
L | 40 – 50 nm | 22 - 32 |
XL | 50 – 60 nm | 32 - 39 |
XXL | 60 – 70 nm | 39 - 46 |







- Waischkies, C. et al. (2017) SPIO-enhanced MRI as a nondestructive in vivo method to assess vascularization of 3D Degrapol® scaffolds planted on the Chorioallantoic membrane of the chick embryo in ovo. Matters Select, DOI: 10.19185/matters.201710000003.
- Jones, J. et al. (2015) Mesenchymal Stem Cells Improve Motor Functions and Decrease Neurodegeneration in Ataxic Mice. Mol. Ther. 23(1): 130–138
- Lohrke, J. et al. (2008) Characterization of superparamagnetic iron oxide nanoparticles by asymmetrical flow-field-flow-fractionation. Nanomedicine 3: 437-452.
- Ludwig, F. et al. (2012) Optimization of Magnetic Nanoparticles for Magnetic Particle Imaging. IEEE Transactions on Magnetics. 48(11): 3780-3783.